About Origami Assays
Origami assays grew out of Dr. Woolf's long term project for developing multiplex screens for the pharmaceutical industry blended with a passion for small scale distributed science.
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Peter Woolf, PhD
Dr. Woolf's research focuses on bioinformatics and information theory. He has worked in both academic and industrial settings on topics ranging from systems biology, computer science, synthetic biology, control theory, automation, and energy efficiency. He obtained his PhD in chemical engineering from the University of Michigan, and did his postdoctoral work in developmental biology and bioengineering at Harvard University and MIT respectively. Currently, Dr. Woolf is leading a number of startup companies focused on bioinformatics and energy efficient design.
Relating to Origami Assays in particular, Dr. Woolf has published a number of articles about multiplex screening for pharmaceutical drug discovery and informatic screening:
Kainkaryam RM Woolf PJ. (2008). poolHiTS: a shifted transversal design based pooling strategy for high-throughput drug screening. BMC Bioinformatics, 9:256. doi: 10.1186/1471-2105-9-256.
Kainkaryam RM, Woolf PJ (2009) Pooling in high-throughput drug screening,
Curr Opin Drug Discov Devel. 12(3):339-50.
Kainkaryam RM, Bruex A, Gilbert AC, Schiefelbein J, Woolf PJ. (2010) poolMC: smart pooling of mRNA samples in microarray experiments. BMC Bioinformatics. 11:299. doi: 10.1186/1471-2105-11-299.
Kainkaryam RM, Bruex A, Woolf PJ, Schiefelbein J. (2012) Smart pooling of mRNA samples for efficient transcript profiling. Methods Mol Biol. 876:189-94. doi: 10.1007/978-1-61779-809-2_15.